Caffeine - Revision history

Admin: add rats

2021-11-10T10:24:53Z

add rats

← Older revision		Revision as of 10:24, 10 November 2021
Line 4:		Line 4:

	While caffeine both does induce a number of scientifically validated positive and negative effects on humans for a short time after consumption, withdrawal symptoms are possible in the case of caffeine dependence and are recognized by the ICD-11 and DSM-5.		While caffeine both does induce a number of scientifically validated positive and negative effects on humans for a short time after consumption, withdrawal symptoms are possible in the case of caffeine dependence and are recognized by the ICD-11 and DSM-5.

			Caffeine is also shown to reduce time spent in SWS/REM<ref name="ratsCaffeine" /> in rats.

	There are large genetically based differences in caffeine clearance time in the body<ref name="adenosine4" />, which might account for anecdotal accounts of varying sensitivity and prolonged effects of caffeine after ingestion.		There are large genetically based differences in caffeine clearance time in the body<ref name="adenosine4" />, which might account for anecdotal accounts of varying sensitivity and prolonged effects of caffeine after ingestion.
Line 82:		Line 84:
	<ref name="bev9">{{cite web \|url=http://www.elmwoodinn.com/about/caffeine.html \|title=Too Easy to be True. De-bunking the At-Home Decaffeination Myth \|last=Richardson \|first=Bruce \|name-list-style=vanc \|year=2009 \|publisher=Elmwood Inn \|access-date=12 January 2012 \|url-status=dead \|archive-url=https://web.archive.org/web/20111227192924/http://elmwoodinn.com/about/caffeine.html \|archive-date=27 December 2011 \|df=dmy-all}}</ref>		<ref name="bev9">{{cite web \|url=http://www.elmwoodinn.com/about/caffeine.html \|title=Too Easy to be True. De-bunking the At-Home Decaffeination Myth \|last=Richardson \|first=Bruce \|name-list-style=vanc \|year=2009 \|publisher=Elmwood Inn \|access-date=12 January 2012 \|url-status=dead \|archive-url=https://web.archive.org/web/20111227192924/http://elmwoodinn.com/about/caffeine.html \|archive-date=27 December 2011 \|df=dmy-all}}</ref>
	<ref name="rats">{{cite journal \|vauthors=Radulovacki M, Virus RM, Djuricic-Nedelson M, Green RD \|date=February 1984 \|title=Adenosine analogs and sleep in rats \|url=https://jpet.aspetjournals.org/content/228/2/268.short \|journal=Journal of Pharmacology and Experimental Therapeutics \|volume=228 \|issue=2 \|pages=268-274}}</ref>		<ref name="rats">{{cite journal \|vauthors=Radulovacki M, Virus RM, Djuricic-Nedelson M, Green RD \|date=February 1984 \|title=Adenosine analogs and sleep in rats \|url=https://jpet.aspetjournals.org/content/228/2/268.short \|journal=Journal of Pharmacology and Experimental Therapeutics \|volume=228 \|issue=2 \|pages=268-274}}</ref>
			<ref name="ratsCaffeine">{{cite journal \|vauthors=Jang H, Jung J, Jang I, Jang K, Kim S, Ha J, Lee M \|date=2012 \|title=L-theanine partially counteracts caffeine-induced sleep disturbances in rats \|url=https://pubmed.ncbi.nlm.nih.gov/22285321/ \|journal=Pharmocology, biochemistry, and behavior \|volume=101 \|issue=2 \|doi=10.1016/j.pbb.2012.01.011}}</ref>
	}}		}}

Admin: added ref templates

2020-12-21T11:37:00Z

added ref templates

← Older revision		Revision as of 11:37, 21 December 2020
Line 1:		Line 1:
	Caffeine is the most widespread psychoactive drug in the world <ref~~>Burchfield G (1997). Hopes M (ed.). [https://web.archive.org/web/20090726194701/http://www.~~abc.net~~.au/quantum/poison/caffeine/caffeine.htm~~ "What's your poison: caffeine".] Australian Broadcasting Corporation. Archived from the [http://www.abc.net.au/quantum/poison/caffeine/caffeine.htm original] on 26 July 2009. Retrieved 15 January 2014.</~~ref~~> and is contained in large quantities in coffee and, in lower concentration, in other beverages that are regularly consumed to temporally ward of drowsiness or increase mental performance.		Caffeine is the most widespread psychoactive drug in the world<ref name="abc.net" /> and is contained in large quantities in coffee and, in lower concentration, in other beverages that are regularly consumed to temporally ward of drowsiness or increase mental performance.

	The main mechanism <ref~~>https://www.ncbi.nlm.nih.gov/pmc~~/~~articles/PMC2769007/</ref~~> at work with caffeine to achieve the alleviation of drowsiness is by blocking adenosine receptors in the brain, due to a similar chemical structure as adenosine<ref>"~~The structure of caffeine is very similar to adenosine, which allows it to bind to (all) the A1, A2a, A2b, and A3 ARs.~~"~~[https://www.sciencedirect.com/science~~/~~article/pii/S0278584618301726 Julius Schuster,Ellen in Progress in Neuro-Psychopharmacology and Biological PsychiatryS.Mitchell] </ref~~>, that are a part of the sleep regulation mechanism.		The main mechanism<ref name="pmid20190965" /> at work with caffeine to achieve the alleviation of drowsiness is by blocking adenosine receptors in the brain, due to a similar chemical structure as adenosine<ref name="adenosine3" />, that are a part of the sleep regulation mechanism.

	While caffeine both does induce a number of scientifically validated positive and negative effects on humans for a short time after consumption, withdrawal symptoms are possible in the case of caffeine dependence and are recognized by the ICD-11 and DSM-5.		While caffeine both does induce a number of scientifically validated positive and negative effects on humans for a short time after consumption, withdrawal symptoms are possible in the case of caffeine dependence and are recognized by the ICD-11 and DSM-5.

	There are large genetically based differences in caffeine clearance time in the body<ref>"CYP1A2 gene polymorphism has been shown to alter the expression or activity of the CYP1A2 enzyme (Rasmussen et al., 2002), which subsequently results in a large individual variability of caffeine clearance." ~~in "[https://www.sciencedirect.com/science/article/pii/S0278584618301726 Progress in Neuro-Psychopharmacology and Biological Psychiatry]" by JuliusSchuster, Ellen S.Mitchell<~~/~~ref~~>, which might account for anecdotal accounts of varying sensitivity and prolonged effects of caffeine after ingestion.		There are large genetically based differences in caffeine clearance time in the body<ref name="adenosine4" />, which might account for anecdotal accounts of varying sensitivity and prolonged effects of caffeine after ingestion.

	==Caffeinated beverages==		==Caffeinated beverages==
	Average caffeine content in beverages<ref~~>[https://web.archive.org/web/20070614144016/http://www.cspinet.org/nah/caffeine/caffeine_content.htm~~ "~~Caffeine Content of Food and Drugs~~"]. Nutrition Action Health Newsletter. Center for Science in the Public Interest. 1996. Archived from [http://www.cspinet.org/nah/caffeine/caffeine_content.htm the original] on 14 June 2007. Retrieved 3 August 2009.</~~ref~~><ref~~>[http://www.erowid.org/chemicals/caffeine/caffeine_info1.shtml~~ "~~Caffeine Content of Beverages, Foods, & Medications~~"~~.] The Vaults of Erowid. 7 July 2006. Retrieved 3 August 2009.<~~/~~ref~~><ref~~>[http://www.caffeineinformer.com/the-caffeine-database~~ "~~Caffeine Content of Drinks~~"~~]. Caffeine Informer. Retrieved 8 December 2013.<~~/~~ref~~><ref~~>Chin JM, Merves ML, Goldberger BA, Sampson-Cone A, Cone EJ (October 2008). [https://doi.org/10.1093%2Fjat%2F32.8.702~~ "~~Caffeine content of brewed teas~~"~~]. Journal of Analytical Toxicology. 32 (8): 702–4. [https://doi.org~~/~~10.1093%2Fjat%2F32.8.702 doi:10.1093/jat/32.8.702]. PMID 19007524</ref~~><ref~~>Richardson B (2009). [https://web.archive.org/web/20111227192924/http://elmwoodinn.com/about/caffeine.html~~ "~~Too Easy to be True. De-bunking the At-Home Decaffeination Myth~~"~~]. Elmwood Inn. Archived from the original on 27 December 2011. Retrieved 12 January 2012.<~~/~~ref~~>		Average caffeine content in beverages<ref name="bev5" /><ref name="bev6" /><ref name="bev7" /><ref name="bev8" /><ref name="bev9" />
	{\| class="wikitable sortable"		{\| class="wikitable sortable"
	\|+		\|+
Line 68:		Line 68:
	==Recommendations==		==Recommendations==

	For the purpose of adapting to Polyphasic sleep, the community discourages the intake of caffeinated beverages due to the ability of caffeine to disrupt sleep, decrease the amount of SWS sleep<ref~~>Adenosine analogs and sleep in rats.~~		For the purpose of adapting to Polyphasic sleep, the community discourages the intake of caffeinated beverages due to the ability of caffeine to disrupt sleep, decrease the amount of SWS sleep<ref name="rats" /> in a sleep block and mask sleep deprivation symptoms during the adaptation period. The long half life of caffeine (particularly as contained in coffee), significantly outlasts both the perceptible cognitive boost and the inevitable following caffeine crash, proceeding to effect the next sleep block in a subtle but negative way.
	~~Radulovacki M, Virus RM, Djuricic-Nedelson M, Green RD~~
	~~J Pharmacol Exp Ther. 1984 Feb; 228(2):268-74.[https://scholar.google.com/scholar_lookup?journal~~=~~J.+Pharmacol.+Exp.+Ther&title=Adenosine+analogs+and+sleep+in+~~rats~~&author=M+Radulovacki&author=RM+Virus&author=M+Djuricic-Nedelson&author=RD+Green&volume=228&publication_year=1984&pages=268-274&pmid=6694111&]<~~/~~ref~~> in a sleep block and mask ~~[[wikipedia:Sleep_deprivation\|~~sleep deprivation]] symptoms during the adaptation period. The long half life of caffeine (particularly as contained in coffee), significantly outlasts both the perceptible cognitive boost and the inevitable following caffeine crash, proceeding to effect the next sleep block in a subtle but negative way.

	==References==		==References==
	<~~references~~ />		{{reflist\|refs=
			<ref name="abc.net">{{cite news \|title=What's your poison: caffeine \|publisher=Australian Broadcasting Corporation \|year=1997 \|url=http://www.abc.net.au/quantum/poison/caffeine/caffeine.htm \|access-date=15 January 2014 \|first = Geoffrey \|last = Burchfield \|editor-first = Meredith \|editor-last = Hopes \|name-list-style=vanc \|archive-url=https://web.archive.org/web/20090726194701/http://www.abc.net.au/quantum/poison/caffeine/caffeine.htm \|archive-date=26 July 2009 \|url-status=dead \|df=dmy-all}}</ref>
			<ref name="pmid20190965">{{cite journal \|vauthors=Bjorness TE, Greene RW \|date=September 2009 \|title=Adenosine and Sleep \|url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769007/ \|journal=Current Neuropharmacology \|volume=7 \|issue=3 \|pages=238-245 \|doi=10.2174/157015909789152182 \|pmc=2769007 \|pmid=20190965}}</ref>
			<ref name="adenosine3">"The structure of caffeine is very similar to adenosine, which allows it to bind to (all) the A1, A2a, A2b, and A3 ARs." in "[https://www.sciencedirect.com/science/article/pii/S0278584618301726 Progress in Neuro-Psychopharmacology and Biological Psychiatry]" by JuliusSchuster, Ellen S.Mitchell</ref>
			<ref name="adenosine4">"CYP1A2 gene polymorphism has been shown to alter the expression or activity of the CYP1A2 enzyme (Rasmussen et al., 2002), which subsequently results in a large individual variability of caffeine clearance." in "[https://www.sciencedirect.com/science/article/pii/S0278584618301726 Progress in Neuro-Psychopharmacology and Biological Psychiatry]" by JuliusSchuster, Ellen S.Mitchell</ref>
			<ref name="bev5">{{cite web \|title=Caffeine Content of Food and Drugs \|website=Nutrition Action Health Newsletter \|publisher=Center for Science in the Public Interest \|year=1996 \|url=http://www.cspinet.org/nah/caffeine/caffeine_content.htm \|archive-url=https://web.archive.org/web/20070614144016/http://www.cspinet.org/nah/caffeine/caffeine_content.htm \|archive-date=14 June 2007 \|access-date=3 August 2009}}</ref>
			<ref name="bev6">{{cite web \|title=Caffeine Content of Beverages, Foods, & Medications \|publisher=The Vaults of Erowid \|date=7 July 2006 \|url=http://www.erowid.org/chemicals/caffeine/caffeine_info1.shtml \|access-date=3 August 2009}}</ref>
			<ref name="bev7">{{cite web \|url=http://www.caffeineinformer.com/the-caffeine-database \|title=Caffeine Content of Drinks \|website=Caffeine Informer \|access-date=8 December 2013}}</ref>
			<ref name="bev8">{{cite journal \|vauthors=Chin JM, Merves ML, Goldberger BA, Sampson-Cone A, Cone EJ \|title=Caffeine content of brewed teas \|journal=Journal of Analytical Toxicology \|volume=32 \|issue=8 \|pages=702–704 \|date=October 2008 \|pmid=19007524 \|doi=10.1093/jat/32.8.702 \|doi-access=free}}</ref>
			<ref name="bev9">{{cite web \|url=http://www.elmwoodinn.com/about/caffeine.html \|title=Too Easy to be True. De-bunking the At-Home Decaffeination Myth \|last=Richardson \|first=Bruce \|name-list-style=vanc \|year=2009 \|publisher=Elmwood Inn \|access-date=12 January 2012 \|url-status=dead \|archive-url=https://web.archive.org/web/20111227192924/http://elmwoodinn.com/about/caffeine.html \|archive-date=27 December 2011 \|df=dmy-all}}</ref>
			<ref name="rats">{{cite journal \|vauthors=Radulovacki M, Virus RM, Djuricic-Nedelson M, Green RD \|date=February 1984 \|title=Adenosine analogs and sleep in rats \|url=https://jpet.aspetjournals.org/content/228/2/268.short \|journal=Journal of Pharmacology and Experimental Therapeutics \|volume=228 \|issue=2 \|pages=268-274}}</ref>
			}}

	==See also==		==See also==

Admin: Text replacement - "sleep deprivation" to "sleep deprivation"

2020-12-20T16:03:18Z

Text replacement - "sleep deprivation" to "sleep deprivation"

← Older revision		Revision as of 16:03, 20 December 2020
Line 70:		Line 70:
	For the purpose of adapting to Polyphasic sleep, the community discourages the intake of caffeinated beverages due to the ability of caffeine to disrupt sleep, decrease the amount of SWS sleep<ref>Adenosine analogs and sleep in rats.		For the purpose of adapting to Polyphasic sleep, the community discourages the intake of caffeinated beverages due to the ability of caffeine to disrupt sleep, decrease the amount of SWS sleep<ref>Adenosine analogs and sleep in rats.
	Radulovacki M, Virus RM, Djuricic-Nedelson M, Green RD		Radulovacki M, Virus RM, Djuricic-Nedelson M, Green RD
	J Pharmacol Exp Ther. 1984 Feb; 228(2):268-74.[https://scholar.google.com/scholar_lookup?journal=J.+Pharmacol.+Exp.+Ther&title=Adenosine+analogs+and+sleep+in+rats&author=M+Radulovacki&author=RM+Virus&author=M+Djuricic-Nedelson&author=RD+Green&volume=228&publication_year=1984&pages=268-274&pmid=6694111&]</ref> in a sleep block and mask sleep deprivation symptoms during the adaptation period. The long half life of caffeine (particularly as contained in coffee), significantly outlasts both the perceptible cognitive boost and the inevitable following caffeine crash, proceeding to effect the next sleep block in a subtle but negative way.		J Pharmacol Exp Ther. 1984 Feb; 228(2):268-74.[https://scholar.google.com/scholar_lookup?journal=J.+Pharmacol.+Exp.+Ther&title=Adenosine+analogs+and+sleep+in+rats&author=M+Radulovacki&author=RM+Virus&author=M+Djuricic-Nedelson&author=RD+Green&volume=228&publication_year=1984&pages=268-274&pmid=6694111&]</ref> in a sleep block and mask [[wikipedia:Sleep_deprivation\|sleep deprivation]] symptoms during the adaptation period. The long half life of caffeine (particularly as contained in coffee), significantly outlasts both the perceptible cognitive boost and the inevitable following caffeine crash, proceeding to effect the next sleep block in a subtle but negative way.

	==References==		==References==

Admin: Text replacement - "{{Polyphasic Lifestyle}}" to "{{TNT|Polyphasic Lifestyle}}"

2020-12-12T08:48:29Z

Text replacement - "{{Polyphasic Lifestyle}}" to "{{TNT|Polyphasic Lifestyle}}"

← Older revision		Revision as of 08:48, 12 December 2020
Line 78:		Line 78:
	[https://coffeecalc.cc/ Caffeine half-life calculator]		[https://coffeecalc.cc/ Caffeine half-life calculator]

	{{Polyphasic Lifestyle}}		{{TNT\|Polyphasic Lifestyle}}

Admin at 08:46, 12 December 2020

2020-12-12T08:46:44Z

← Older revision		Revision as of 08:46, 12 December 2020
Line 77:		Line 77:
	==See also==		==See also==
	[https://coffeecalc.cc/ Caffeine half-life calculator]		[https://coffeecalc.cc/ Caffeine half-life calculator]

			{{Polyphasic Lifestyle}}

>Yu: added reference

2020-12-06T07:08:08Z

added reference

← Older revision		Revision as of 07:08, 6 December 2020
Line 5:		Line 5:
	While caffeine both does induce a number of scientifically validated positive and negative effects on humans for a short time after consumption, withdrawal symptoms are possible in the case of caffeine dependence and are recognized by the ICD-11 and DSM-5.		While caffeine both does induce a number of scientifically validated positive and negative effects on humans for a short time after consumption, withdrawal symptoms are possible in the case of caffeine dependence and are recognized by the ICD-11 and DSM-5.

	There are large genetically based differences in caffeine clearance time in the body<ref>"CYP1A2 gene polymorphism has been shown to alter the expression or activity of the CYP1A2 enzyme (Rasmussen et al., 2002), which subsequently results in a large individual variability of caffeine clearance."</ref>, which might account for anecdotal accounts of varying sensitivity and prolonged effects of caffeine after ingestion.		There are large genetically based differences in caffeine clearance time in the body<ref>"CYP1A2 gene polymorphism has been shown to alter the expression or activity of the CYP1A2 enzyme (Rasmussen et al., 2002), which subsequently results in a large individual variability of caffeine clearance." in "[https://www.sciencedirect.com/science/article/pii/S0278584618301726 Progress in Neuro-Psychopharmacology and Biological Psychiatry]" by JuliusSchuster, Ellen S.Mitchell</ref>, which might account for anecdotal accounts of varying sensitivity and prolonged effects of caffeine after ingestion.

	==Caffeinated beverages==		==Caffeinated beverages==

>Yu at 07:05, 6 December 2020

2020-12-06T07:05:47Z

← Older revision		Revision as of 07:05, 6 December 2020
Line 4:		Line 4:

	While caffeine both does induce a number of scientifically validated positive and negative effects on humans for a short time after consumption, withdrawal symptoms are possible in the case of caffeine dependence and are recognized by the ICD-11 and DSM-5.		While caffeine both does induce a number of scientifically validated positive and negative effects on humans for a short time after consumption, withdrawal symptoms are possible in the case of caffeine dependence and are recognized by the ICD-11 and DSM-5.

			There are large genetically based differences in caffeine clearance time in the body<ref>"CYP1A2 gene polymorphism has been shown to alter the expression or activity of the CYP1A2 enzyme (Rasmussen et al., 2002), which subsequently results in a large individual variability of caffeine clearance."</ref>, which might account for anecdotal accounts of varying sensitivity and prolonged effects of caffeine after ingestion.

	==Caffeinated beverages==		==Caffeinated beverages==

>Yu: added a reference

2020-12-06T06:44:31Z

added a reference

← Older revision		Revision as of 06:44, 6 December 2020
Line 1:		Line 1:
	Caffeine is the most widespread psychoactive drug in the world <ref>Burchfield G (1997). Hopes M (ed.). [https://web.archive.org/web/20090726194701/http://www.abc.net.au/quantum/poison/caffeine/caffeine.htm "What's your poison: caffeine".] Australian Broadcasting Corporation. Archived from the [http://www.abc.net.au/quantum/poison/caffeine/caffeine.htm original] on 26 July 2009. Retrieved 15 January 2014.</ref> and is contained in large quantities in coffee and, in lower concentration, in other beverages that are regularly consumed to temporally ward of drowsiness or increase mental performance.		Caffeine is the most widespread psychoactive drug in the world <ref>Burchfield G (1997). Hopes M (ed.). [https://web.archive.org/web/20090726194701/http://www.abc.net.au/quantum/poison/caffeine/caffeine.htm "What's your poison: caffeine".] Australian Broadcasting Corporation. Archived from the [http://www.abc.net.au/quantum/poison/caffeine/caffeine.htm original] on 26 July 2009. Retrieved 15 January 2014.</ref> and is contained in large quantities in coffee and, in lower concentration, in other beverages that are regularly consumed to temporally ward of drowsiness or increase mental performance.

	The main mechanism <ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769007/</ref> at work with caffeine to achieve the alleviation of drowsiness is by blocking adenosine receptors in the brain, due to a similar chemical structure as adenosine<ref>The ~~main effect~~ of caffeine ~~can be attributed~~ to ~~its antagonistic effect on the~~ adenosine ~~receptors~~ (ARs). </ref>, that are a part of the sleep regulation mechanism.		The main mechanism <ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769007/</ref> at work with caffeine to achieve the alleviation of drowsiness is by blocking adenosine receptors in the brain, due to a similar chemical structure as adenosine<ref>"The structure of caffeine is very similar to adenosine, which allows it to bind to (all) the A1, A2a, A2b, and A3 ARs."[https://www.sciencedirect.com/science/article/pii/S0278584618301726 Julius Schuster,Ellen in Progress in Neuro-Psychopharmacology and Biological PsychiatryS.Mitchell] </ref>, that are a part of the sleep regulation mechanism.

	While caffeine both does induce a number of scientifically validated positive and negative effects on humans for a short time after consumption, withdrawal symptoms are possible in the case of caffeine dependence and are recognized by the ICD-11 and DSM-5.		While caffeine both does induce a number of scientifically validated positive and negative effects on humans for a short time after consumption, withdrawal symptoms are possible in the case of caffeine dependence and are recognized by the ICD-11 and DSM-5.

>Yu at 06:39, 6 December 2020

2020-12-06T06:39:03Z

← Older revision		Revision as of 06:39, 6 December 2020
Line 1:		Line 1:
	Caffeine is the most widespread psychoactive drug in the world <ref>Burchfield G (1997). Hopes M (ed.). [https://web.archive.org/web/20090726194701/http://www.abc.net.au/quantum/poison/caffeine/caffeine.htm "What's your poison: caffeine".] Australian Broadcasting Corporation. Archived from the [http://www.abc.net.au/quantum/poison/caffeine/caffeine.htm original] on 26 July 2009. Retrieved 15 January 2014.</ref> and is contained in large quantities in coffee and, in lower concentration, in other beverages that are regularly consumed to temporally ward of drowsiness or increase mental performance.		Caffeine is the most widespread psychoactive drug in the world <ref>Burchfield G (1997). Hopes M (ed.). [https://web.archive.org/web/20090726194701/http://www.abc.net.au/quantum/poison/caffeine/caffeine.htm "What's your poison: caffeine".] Australian Broadcasting Corporation. Archived from the [http://www.abc.net.au/quantum/poison/caffeine/caffeine.htm original] on 26 July 2009. Retrieved 15 January 2014.</ref> and is contained in large quantities in coffee and, in lower concentration, in other beverages that are regularly consumed to temporally ward of drowsiness or increase mental performance.

	The main mechanism <ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769007/</ref> at work with caffeine to achieve the alleviation of drowsiness is by blocking adenosine receptors in the brain that are a part of the sleep regulation mechanism.		The main mechanism <ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769007/</ref> at work with caffeine to achieve the alleviation of drowsiness is by blocking adenosine receptors in the brain, due to a similar chemical structure as adenosine<ref>The main effect of caffeine can be attributed to its antagonistic effect on the adenosine receptors (ARs). </ref>, that are a part of the sleep regulation mechanism.

	While caffeine both does induce a number of scientifically validated positive and negative effects on humans for a short time after consumption, withdrawal symptoms are possible in the case of caffeine dependence and are recognized by the ICD-11 and DSM-5.		While caffeine both does induce a number of scientifically validated positive and negative effects on humans for a short time after consumption, withdrawal symptoms are possible in the case of caffeine dependence and are recognized by the ICD-11 and DSM-5.

Admin: /* Caffeinated beverages */

2020-12-06T03:45:04Z

Caffeinated beverages

← Older revision		Revision as of 03:45, 6 December 2020
Line 59:		Line 59:
	\|320		\|320
	\|}		\|}
			Note:
			Caffeine content in tea can vary significantly based on leaf type and steeping time.

			Detailed info on [https://www.caffeineinformer.com/caffeine-content/green-tea Green tea] and [https://www.caffeineinformer.com/caffeine-content/tea-brewed Black tea].

	==Recommendations==		==Recommendations==